Brief Information of the Compound and Protein
Compound Name
2-(2,6-dimethoxypyridin-3-yl)-6-{[(2S)-1-hydroxy-3-phenylpropan-2-yl]amino}-N-(2-phenoxyethyl)pyridine-3-carboxamide
    Show/Hide
PubChem ID
CID: 25198729
SID: 92309414
Canonical SMILES
COc1ccc(c(OC)n1)-c1nc(N[C@H](CO)Cc2ccccc2)ccc1C(=O)NCCOc1ccccc1
    Show/Hide
Compound Formula C30H32N4O5
Compound Structure
Protein Name
Extracellular calcium-sensing receptor
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
>
Ion receptor (family C GPCR)
>
Calcium sensing receptor
>
Calcium sensing receptor
Uniprot ID
P41180
Gene Name
CASR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 140 nM
   TI
   LI
   LO
   TS