Brief Information of the Compound and Protein
Compound Name
2-(5-(naphthalen-1-ylmethylthio)-1,3,4-thiadiazol-2-ylthio)acetic acid
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PubChem ID
CID: 853224
SID: 50138044
Canonical SMILES
OC(=O)CSc1nnc(SCc2cccc3ccccc23)s1
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Compound Formula C15H12N2O2S3
Compound Structure
Protein Name
Free fatty acid receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
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Free fatty acid receptor
Uniprot ID
O14842
Gene Name
FFAR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL001022 HEK293EM Homo sapiens (Human)  5
1
EC50 = 970 nM
   TI
   LI
   LO
   TS
2
EC50 = 1800 nM
   TI
   LI
   LO
   TS
3
EC50 = 3600 nM
   TI
   LI
   LO
   TS
4
EC50 = 4300 nM
   TI
   LI
   LO
   TS
5
EC50 >= 100000 nM
   TI
   LI
   LO
   TS