Brief Information of the Compound and Protein
Compound Name
(1R,S)-8-trifluoromethyl-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine
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PubChem ID
CID: 10105208
SID: 15093320
Canonical SMILES
CC1CNCCc2ccc(cc12)C(F)(F)F
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Compound Formula C12H14F3N
Compound Structure
Protein Name
5-hydroxytryptamine receptor 2B
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P41595
Gene Name
HTR2B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
EC50 = 380 nM
   TI
   LI
   LO
   TS
2
EC50 = 794.33 nM
   TI
   LI
   LO
   TS