Brief Information of the Compound and Protein
Compound Name
(1R,S)-8-chloro-7-fluoro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine
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PubChem ID
CID: 9990808
SID: 14969416
Canonical SMILES
CC1CNCCc2cc(F)c(Cl)cc12
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Compound Formula C11H13ClFN
Compound Structure
Protein Name
5-hydroxytryptamine receptor 2B
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P41595
Gene Name
HTR2B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
EC50 = 316.23 nM
   TI
   LI
   LO
   TS
2
EC50 = 360 nM
   TI
   LI
   LO
   TS