Brief Information of the Compound and Protein
Compound Name
1-(isoquinolin-5-yl)-3-(2-(4-methoxyphenyl)-3-phenylpropyl)urea
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PubChem ID
CID: 10454306
SID: 15476009
Canonical SMILES
COc1ccc(cc1)C(CNC(=O)Nc1cccc2cnccc12)Cc1ccccc1
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Compound Formula C26H25N3O2
Compound Structure
Protein Name
Transient receptor potential cation channel subfamily V member 1
Protein Classification
Ion channel
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Voltage-gated ion channel
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Transient receptor potential channel
Uniprot ID
Q8NER1
Gene Name
TRPV1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 14 nM
   TI
   LI
   LO
   TS
2
Ki = 6 nM
   TI
   LI
   LO
   TS