Brief Information of the Compound and Protein
Compound Name
2-(2,4-Dichloro-phenoxy)-N-(4-methyl-2-morpholin-4-yl-quinolin-6-yl)-acetamide
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PubChem ID
CID: 4219492
SID: 16722142
Canonical SMILES
Cc1cc(nc2ccc(NC(=O)COc3ccc(Cl)cc3Cl)cc12)N1CCOCC1
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Compound Formula C22H21Cl2N3O3
Compound Structure
Protein Name
Melanin-concentrating hormone receptor 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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MCH receptor
Uniprot ID
Q99705
Gene Name
MCHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  3
1
IC50 = 5.5 nM
   TI
   LI
   LO
   TS
2
IC50 = 15.4 nM
   TI
   LI
   LO
   TS
3
IC50 = 59 nM
   TI
   LI
   LO
   TS