Brief Information of the Compound and Protein
Compound Name
(E)-N-(2-{[(2-Dimethylamino-ethyl)-methyl-amino]-methyl}-quinolin-6-yl)-3-(4-trifluoromethoxy-phenyl)-acrylamide
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PubChem ID
CID: 11568782
SID: 16671057
Canonical SMILES
CN(C)CCN(C)c1ccc2cc(NC(=O)\C=C\c3ccc(OC(F)(F)F)cc3)ccc2n1
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Compound Formula C24H25F3N4O2
Compound Structure
Protein Name
Melanin-concentrating hormone receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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MCH receptor
Uniprot ID
Q99705
Gene Name
MCHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  2
1
IC50 = 29 nM
   TI
   LI
   LO
   TS
2
IC50 = 174 nM
   TI
   LI
   LO
   TS