Brief Information of the Compound and Protein
Compound Name
2-(3-Phenyl-2-piperidin-1-yl-3,4-dihydro-quinazolin-4-yl)-N-[4-(toluene-4-sulfonylamino)-benzyl]-acetamide
    Show/Hide
PubChem ID
CID: 10031616
SID: 15013222
Canonical SMILES
Cc1ccc(cc1)S(=O)(=O)Nc1ccc(CNC(=O)CC2N(C(=Nc3ccccc23)N2CCCCC2)c2ccccc2)cc1
    Show/Hide
Compound Formula C35H37N5O3S
Compound Structure
Protein Name
Voltage-dependent T-type calcium channel subunit alpha-1G
Protein Classification
Ion channel
>
Voltage-gated ion channel
>
Voltage-gated calcium channel
Uniprot ID
O43497
Gene Name
CACNA1G
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  3
1
IC50 = 169.82 nM
   TI
   LI
   LO
   TS
2
IC50 = 170 nM
   TI
   LI
   LO
   TS
3
IC50 = 250 nM
   TI
   LI
   LO
   TS