Brief Information of the Compound and Protein
Compound Name
9-Dimethylamino-3-p-tolyl-3H-pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-one
    Show/Hide
PubChem ID
CID: 744275
SID: 16800221
Canonical SMILES
CN(C)c1ccnc2sc3c(ncn(-c4ccc(C)cc4)c3=O)c12
    Show/Hide
Compound Formula C18H16N4OS
Compound Structure
Protein Name
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
>
Small molecule receptor (family C GPCR)
>
Neurotransmitter receptor (family C GPCR)
>
Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000094 1321N1 Homo sapiens (Human)  1
1
IC50 = 890 nM
   TI
   LI
   LO
   TS