Brief Information of the Compound and Protein
Compound Name
(Z)-1-((5-Fluoro-6-methoxy-1H-indol-3-yl)methylene)-6-methyl-4-thioxo-4,5-dihydrofuro[3,4-c]pyridin-3(1H)-one
    Show/Hide
PubChem ID
CID: 25156695
SID: 57250749
Canonical SMILES
COc1cc2[nH]c(\C=C3/OC(=O)c4c3cc(C)[nH]c4=S)cc2cc1F
    Show/Hide
Compound Formula C18H13FN2O3S
Compound Structure
Protein Name
Perforin-1
Protein Classification
Ion channel
>
Other ion channel
>
Pore-forming toxins (proteins and peptides)
Uniprot ID
P14222
Gene Name
PRF1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000001 Jurkat Homo sapiens (Human)  1
1
IC50 = 6300 nM
   TI
   LI
   LO
   TS