Brief Information of the Compound and Protein
Compound Name
2-{3-(2-Amino-ethyl-guanidino)-4-[2-amino-3-(4-fluoro-phenyl)-propionyl]-2-oxo-piperazin-1-yl}-N-methyl-3-naphthalen-2-yl-propionamide
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PubChem ID
CID: 25131478
SID: 56455902
Canonical SMILES
CNC(=O)[C@H](Cc1ccc2ccccc2c1)N1CCN(C(=O)[C@H](N)Cc2ccc(F)cc2)[C@@H](C/C=N/NC(=N)N)C1=O
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Compound Formula C30H35FN8O3
Compound Structure
Protein Name
Melanocortin receptor 4
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Melanocortin receptor
Uniprot ID
P32245
Gene Name
MC4R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
EC50 = 0.9 nM
   TI
   LI
   LO
   TS
2
Ki = 1.4 nM
   TI
   LI
   LO
   TS