Brief Information of the Compound and Protein
Compound Name
 Compound Info 
LY 458545
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 PubChem ID
CID: 11153198
SID: 24724807
Canonical SMILES
OC(=O)[C@@H]1C[C@H]2C[C@H](CC[C@H]2CN1)Oc1ccccc1-c1nnn[nH]1
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Compound Formula C17H21N5O3
Compound Structure
Protein Name
 Protein Info 
Glutamate receptor 2
Protein Classification
Ion channel
>
Ligand-gated ion channel
>
Ionotropic glutamate receptor
>
AMPA receptor
Uniprot ID
P42262
Gene Name
GRIA2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 8260 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 16000 nM