Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-[1-(2,2-Diphenyl-ethyl)-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]-ethanone
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 PubChem ID
CID: 9909783
SID: 14880009
Canonical SMILES
COc1cc2CCN(C(CC(c3ccccc3)c3ccccc3)c2cc1OC)C(C)=O
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Compound Formula C27H29NO3
Compound Structure
Protein Name
 Protein Info 
Melatonin receptor type 1A
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
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Monoamine-derivative receptor (family A GPCR)
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Melatonin receptor
Uniprot ID
P48039
Gene Name
MTNR1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3
 Cell Line Info 
Mus musculus (Mouse)  1
1
Ki < 1000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 > 1000 nM