Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[2-[[[5-amino-1-(4-fluorophenyl)pyrazole-4-carbonyl]amino]methyl]-3,3,3-trifluoro-2-hydroxypropyl]-2-chloro-N-ethylpyridine-3-carboxamide
    Show/Hide
 PubChem ID
CID: 44570183
Canonical SMILES
CCN(CC(O)(CNC(=O)c1cnn(c1N)-c1ccc(F)cc1)C(F)(F)F)C(=O)c1cccnc1Cl
    Show/Hide
Compound Formula C22H21ClF4N6O3
Compound Structure
Protein Name
 Protein Info 
Glucocorticoid receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
>
Nuclear hormone receptor subfamily 3 group C member 1
Uniprot ID
P04150
Gene Name
NR3C1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 794.33 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 39.81 nM