Brief Information of the Compound and Protein
Compound Name
2-(4-chlorophenyl)sulfanyl-4-[(2,6-difluorophenyl)methyl]-5-methyl-1H-pyrimidin-6-one
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PubChem ID
CID: 135429691
Canonical SMILES
Cc1c(Cc2c(F)cccc2F)nc(Sc2ccc(Cl)cc2)[nH]c1=O
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Compound Formula C18H13ClF2N2OS
Compound Structure
Protein Name
Reverse transcriptase/RNaseH
Protein Classification
Enzyme
>
Hydrolase
Uniprot ID
Q72547
Gene Name
POL
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000247 MT-4 Homo sapiens (Human)  3
1
EC50 = 100 nM
   TI
   LI
   LO
   TS
2
EC50 = 8010 nM
   TI
   LI
   LO
   TS
3
EC50 > 66100 nM
   TI
   LI
   LO
   TS