Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[(2,6-dichlorophenyl)methyl]-2-(6-methoxypyridin-3-yl)sulfanyl-5-methyl-1H-pyrimidin-6-one
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 PubChem ID
CID: 135429697
Canonical SMILES
COc1ccc(Sc2nc(Cc3c(Cl)cccc3Cl)c(C)c(=O)[nH]2)cn1
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Compound Formula C18H15Cl2N3O2S
Compound Structure
Protein Name
 Protein Info 
Reverse transcriptase/RNaseH
Protein Classification
Enzyme
>
Hydrolase
Uniprot ID
Q72547
Gene Name
POL
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000247 MT-4
 Cell Line Info 
Homo sapiens (Human)  5
1
EC50 = 2720 nM
   TI
   LI
   LO
   TS
2
EC50 = 6520 nM
   TI
   LI
   LO
   TS
3
EC50 = 8680 nM
   TI
   LI
   LO
   TS
4
EC50 > 61300 nM
   TI
   LI
   LO
   TS
5
EC50 > 61700 nM
   TI
   LI
   LO
   TS