Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[(2,6-difluorophenyl)methyl]-5-methyl-2-phenylsulfanyl-1H-pyrimidin-6-one
    Show/Hide
 PubChem ID
CID: 135429690
SID: 24383279
Canonical SMILES
Cc1c(Cc2c(F)cccc2F)nc(Sc2ccccc2)[nH]c1=O
    Show/Hide
Compound Formula C18H14F2N2OS
Compound Structure
Protein Name
 Protein Info 
Reverse transcriptase/RNaseH
Protein Classification
Enzyme
>
Hydrolase
Uniprot ID
Q72547
Gene Name
POL
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000247 MT-4
 Cell Line Info 
Homo sapiens (Human)  4
1
EC50 = 90 nM
   TI
   LI
   LO
   TS
2
EC50 = 16700 nM
   TI
   LI
   LO
   TS
3
EC50 = 42500 nM
   TI
   LI
   LO
   TS
4
EC50 > 72700 nM
   TI
   LI
   LO
   TS