Brief Information of the Compound and Protein
Compound Name
3,3,3-trifluoro-2-hydroxy-2-[(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)methyl]-N-(4-methyl-1-oxo-2,3-benzoxazin-6-yl)propanamide
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PubChem ID
CID: 11525793
SID: 16627748
Canonical SMILES
COc1cccc2C(CC(O)(C(=O)Nc3ccc4c(c3)c(C)noc4=O)C(F)(F)F)CCCc12
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Compound Formula C24H23F3N2O5
Compound Structure
Protein Name
Glucocorticoid receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
>
Nuclear hormone receptor subfamily 3 group C member 1
Uniprot ID
P04150
Gene Name
NR3C1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549 Homo sapiens (Human)  1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 12.59 nM