Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3,3,3-trifluoro-2-hydroxy-N-(4-methyl-1-oxo-2,3-benzoxazin-6-yl)-2-[[1-(2-methylpropyl)-3,4-dihydro-2H-naphthalen-1-yl]methyl]propanamide
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 PubChem ID
CID: 11591459
SID: 16693949
Canonical SMILES
CC(C)CC1(CC(O)(C(=O)Nc2ccc3c(c2)c(C)noc3=O)C(F)(F)F)CCCc2ccccc12
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Compound Formula C27H29F3N2O4
Compound Structure
Protein Name
 Protein Info 
Glucocorticoid receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
>
Nuclear hormone receptor subfamily 3 group C member 1
Uniprot ID
P04150
Gene Name
NR3C1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549
 Cell Line Info 
Homo sapiens (Human)  3
1
EC50 > 1000 nM
   TI
   LI
   LO
   TS
2
IC50 = 15.85 nM
   TI
   LI
   LO
   TS
3
IC50 = 512.86 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3.467 nM