Brief Information of the Compound and Protein
Compound Name
[1-[4-(2,2-diphenylethylamino)-3-(morpholine-4-carbonyl)phenyl]sulfonylpiperidin-4-yl]-(4-methylpiperazin-1-yl)methanone
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PubChem ID
CID: 9831083
SID: 14790258
Canonical SMILES
CN1CCN(CC1)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc(NCC(c2ccccc2)c2ccccc2)c(c1)C(=O)N1CCOCC1
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Compound Formula C36H45N5O5S
Compound Structure
Protein Name
B1 bradykinin receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Bradykinin receptor
Uniprot ID
P46663
Gene Name
BDKRB1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
Ki = 8 nM
   TI
   LI
   LO
   TS
2
Ki = 10 nM
   TI
   LI
   LO
   TS
CL000790 MR-5 Homo sapiens (Human)  1
1
IC50 = 33 nM
   TI
   LI
   LO
   TS