Brief Information of the Compound and Protein
Compound Name
N-(4,5-dimethyl-1,3-thiazol-2-yl)-15-methyltetracyclo[6.6.2.02,7.09,14]hexadeca-2,4,6,9,11,13-hexaene-15-carboxamide
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PubChem ID
CID: 23596330
Canonical SMILES
Cc1nc(NC(=O)C2(C)CC3c4ccccc4C2c2ccccc32)sc1C
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Compound Formula C23H22N2OS
Compound Structure
Protein Name
Glucocorticoid receptor
Protein Classification
Transcription factor
>
Nuclear receptor
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Nuclear hormone receptor subfamily 3
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Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 1
Uniprot ID
P04150
Gene Name
NR3C1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549 Homo sapiens (Human)  1
1
EC50 = 922.6 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 22.6 nM