Brief Information of the Compound and Protein
Compound Name
4-((1H-imidazol-2-yl)methyl)-1-(biphenyl-4-ylsulfonyl)piperidine
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PubChem ID
CID: 44565848
SID: 99240076
Canonical SMILES
O=S(=O)(N1CCC(Cc2ncc[nH]2)CC1)c1ccc(cc1)-c1ccccc1
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Compound Formula C21H23N3O2S
Compound Structure
Protein Name
5-hydroxytryptamine receptor 2B
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P41595
Gene Name
HTR2B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  2
1
IC50 = 6.5 nM
   TI
   LI
   LO
   TS
2
IC50 = 990 nM
   TI
   LI
   LO
   TS