Brief Information of the Compound and Protein
Compound Name
1-[2-[(1-ethyl-3,4-dihydro-2H-naphthalen-1-yl)methyl]-3,3,3-trifluoro-2-hydroxypropyl]quinolin-4-one
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PubChem ID
CID: 24748958
SID: 49651083
Canonical SMILES
CCC1(CC(O)(Cn2ccc(=O)c3ccccc23)C(F)(F)F)CCCc2ccccc12
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Compound Formula C25H26F3NO2
Compound Structure
Protein Name
Glucocorticoid receptor
Protein Classification
Transcription factor
>
Nuclear receptor
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Nuclear hormone receptor subfamily 3
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Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 1
Uniprot ID
P04150
Gene Name
NR3C1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549 Homo sapiens (Human)  2
1
EC50 > 1000 nM
   TI
   LI
   LO
   TS
2
IC50 = 8.128 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 14.13 nM