Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[(2-chloroquinolin-4-yl)methyl]-3-(1-ethyl-3,4-dihydro-2H-naphthalen-1-yl)-1,1,1-trifluoropropan-2-ol
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 PubChem ID
CID: 24749050
SID: 49651177
Canonical SMILES
CCC1(CC(O)(Cc2cc(Cl)nc3ccccc23)C(F)(F)F)CCCc2ccccc12
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Compound Formula C25H25ClF3NO
Compound Structure
Protein Name
 Protein Info 
Glucocorticoid receptor
Protein Classification
Transcription factor
>
Nuclear receptor
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Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 1
Uniprot ID
P04150
Gene Name
NR3C1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 = 51.29 nM
   TI
   LI
   LO
   TS
2
IC50 = 30.2 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 28.18 nM