Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-amino-6-[2-(1,1'-biphenyl-3-yl)ethyl]-3,6-dimethyl-5,6-dihydropyrimidin-4(3H)-one
    Show/Hide
 PubChem ID
CID: 11638363
SID: 16741601
Canonical SMILES
CN1C(=O)CC(C)(CCc2cccc(c2)-c2ccccc2)N=C1N
    Show/Hide
Compound Formula C20H23N3O
Compound Structure
Protein Name
 Protein Info 
Beta-secretase 1
Protein Classification
Enzyme
>
Protease
>
Aspartic protease
>
Aspartic protease AA clan
>
Aspartic protease A1A subfamily
Uniprot ID
P56817
Gene Name
BACE1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 1700 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1600 nM