Brief Information of the Compound and Protein
Compound Name
2-amino-6-[2-(3'-methoxy-1,1'-biphenyl-3-yl)ethyl]-3-methylpyrimidin-4(3H)-one
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PubChem ID
CID: 11652923
SID: 16756419
Canonical SMILES
COc1cccc(c1)-c1cccc(CCc2cc(=O)n(C)c(N)n2)c1
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Compound Formula C20H21N3O2
Compound Structure
Protein Name
Beta-secretase 1
Protein Classification
Enzyme
>
Protease
>
Aspartic protease
>
Aspartic protease AA clan
>
Aspartic protease A1A subfamily
Uniprot ID
P56817
Gene Name
BACE1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 91000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 5300 nM
2 IC50 = 5700 nM
3 IC50 = 5900 nM