Brief Information of the Compound and Protein
Compound Name
3-methoxy-4-[2-[2-[2-[2-[[4-(1-methyl-3,6-dihydro-2H-pyridin-5-yl)-1,2,5-thiadiazol-3-yl]oxy]ethoxy]ethoxy]ethoxy]ethoxy]-1,2,5-thiadiazole
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PubChem ID
CID: 9913341
SID: 14883769
Canonical SMILES
COc1nsnc1OCCOCCOCCOCCOc1nsnc1C1=CCCN(C)C1
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Compound Formula C19H29N5O6S2
Compound Structure
Protein Name
Muscarinic acetylcholine receptor M1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
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Monoamine receptor
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Acetylcholine receptor
Uniprot ID
P11229
Gene Name
CHRM1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000398 A-9 Mus musculus (Mouse)  4
1
EC50 = 63.1 nM
   TI
   LI
   LO
   TS
2
EC50 = 251.19 nM
   TI
   LI
   LO
   TS
3
EC50 = 1995.26 nM
   TI
   LI
   LO
   TS
4
Ki = 50.12 nM
   TI
   LI
   LO
   TS