Brief Information of the Compound and Protein
Compound Name
2-(6-(4-aminopiperidin-1-yl)pyrimidin-4-ylamino)thiazole-5-carbonitrile
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PubChem ID
CID: 21934657
Canonical SMILES
NC1CCN(CC1)c1cc(Nc2ncc(s2)C#N)ncn1
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Compound Formula C13H15N7S
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 59 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 10 nM