Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-amino-N-tert-butyl-4-(3-methoxyphenyl)-2-methylsulfanylthieno[2,3-d]pyrimidine-6-carboxamide
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 PubChem ID
CID: 9887381
SID: 14854886
Canonical SMILES
COc1cccc(c1)-c1nc(SC)nc2sc(C(=O)NC(C)(C)C)c(N)c12
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Compound Formula C19H22N4O2S2
Compound Structure
Protein Name
 Protein Info 
Thyrotropin receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Glycohormone receptor
>
Glycohormone receptor
Uniprot ID
P16473
Gene Name
TSHR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL001022 HEK293EM
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 6500 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 7700 nM