Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(R)-2-(4-methyl-2-(pyrrolidin-1-yl)pyrimidin-5-yl)-6-(2-(2-methylpyrrolidin-1-yl)ethyl)quinoline
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 PubChem ID
CID: 11647025
SID: 16750422
Canonical SMILES
C[C@@H]1CCCN1CCc1ccc2nc(ccc2c1)-c1cnc(nc1C)N1CCCC1
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Compound Formula C25H31N5
Compound Structure
Protein Name
 Protein Info 
Histamine H3 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Histamine receptor
Uniprot ID
Q9QYN8
Gene Name
HRH3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 = 3.02 nM
   TI
   LI
   LO
   TS
2
Ki = 1.95 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 0.72 nM