Brief Information of the Compound and Protein
Compound Name
4-chloro-2-fluoro-5-({7-[2-(hydroxymethyl)-1,3-thiazol-4-yl]quinolin-4-yl}amino)phenol
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PubChem ID
CID: 25023827
SID: 56377487
Canonical SMILES
OCc1nc(cs1)-c1ccc2c(Nc3cc(O)c(F)cc3Cl)ccnc2c1
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Compound Formula C19H13ClFN3O2S
Compound Structure
Protein Name
Proto-oncogene tyrosine-protein kinase receptor Ret
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase Ret family
Uniprot ID
P07949
Gene Name
RET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 25 nM
   TI
   LI
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