Brief Information of the Compound and Protein
Compound Name
1-{4-[2-({4-[(5-fluoro-2H-1,3-benzodioxol-4-yl)amino]-5-(propan-2-yloxy)quinazolin-7-yl}oxy)ethyl]piperazin-1-yl}ethan-1-one
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PubChem ID
CID: 11974215
SID: 17426081
Canonical SMILES
CC(C)Oc1cc(OCCN2CCN(CC2)C(C)=O)cc2ncnc(Nc3c4OCOc4ccc3F)c12
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Compound Formula C26H30FN5O5
Compound Structure
Protein Name
Proto-oncogene tyrosine-protein kinase Src
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Src family
Uniprot ID
P12931
Gene Name
SRC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  2
1
IC50 = 20 nM
   TI
   LI
   LO
   TS
2
IC50 = 200 nM
   TI
   LI
   LO
   TS