Brief Information of the Compound and Protein
Compound Name
[4-[4-(3,4-dimethylpiperazin-1-yl)anilino]-6-fluoroquinolin-3-yl]methanol
    Show/Hide
PubChem ID
CID: 10317643
SID: 15326899
Canonical SMILES
CC1CN(CCN1C)c1ccc(Nc2c(CO)cnc3ccc(F)cc23)cc1
    Show/Hide
Compound Formula C22H25FN4O
Compound Structure
Protein Name
Alpha-2C adrenergic receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Adrenergic receptor
Uniprot ID
P18825
Gene Name
ADRA2C
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000796 SC-115 Mus musculus (Mouse)  1
1
Ki = 43 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 42.95 nM