Brief Information of the Compound and Protein
Compound Name
(R)-[4-(3,4-dimethylpiperazin-1-yl)phenyl]-(2,3,7,8-tetramethylquinolin-4-yl)amine
    Show/Hide
PubChem ID
CID: 16090623
SID: 24736641
Canonical SMILES
C[C@@H]1CN(CCN1C)c1ccc(Nc2c(C)c(C)nc3c(C)c(C)ccc23)cc1
    Show/Hide
Compound Formula C25H32N4
Compound Structure
Protein Name
Alpha-2C adrenergic receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Adrenergic receptor
Uniprot ID
P18825
Gene Name
ADRA2C
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000796 SC-115 Mus musculus (Mouse)  1
1
Ki = 7.7 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 7.691 nM