Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4aH,5H,6H,7H,8H-cyclohexa[f]indazol-5-yl]propan-2-ol
    Show/Hide
 PubChem ID
CID: 11244720
SID: 16329347
Canonical SMILES
CC(C)(O)[C@H]1CCCC2=Cc3c(C[C@]12C)cnn3-c1ccc(F)cc1
    Show/Hide
Compound Formula C21H25FN2O
Compound Structure
Protein Name
 Protein Info 
Glucocorticoid receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
>
Nuclear hormone receptor subfamily 3 group C member 1
Uniprot ID
P04150
Gene Name
NR3C1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 3 nM
   TI
   LI
   LO
   TS
CL000063 Hep-G2
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 83.5 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1.9 nM