Brief Information of the Compound and Protein
Compound Name
3-Cyano-N-(6-methylpyridin-2-yl)-4-(pyridine-3-yl)-benzamid
    Show/Hide
PubChem ID
CID: 44157256
SID: 85157204
Canonical SMILES
Cc1cccc(NC(=O)c2ccc(-c3cccnc3)c(c2)C#N)n1
    Show/Hide
Compound Formula C19H14N4O
Compound Structure
Protein Name
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
>
Small molecule receptor (family C GPCR)
>
Neurotransmitter receptor (family C GPCR)
>
Metabotropic glutamate receptor
Uniprot ID
P31424
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  1
1
Ki = 2040 nM
   TI
   LI
   LO
   TS
CL000050 HEK293-A Homo sapiens (Human)  1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS