Brief Information of the Compound and Protein
Compound Name
 Compound Info 
pyridin-3-ylmethyl N-[[4-[(2-aminophenyl)carbamoyl]phenyl]methyl]carbamate
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 PubChem ID
CID: 4261
SID: 14804341
Canonical SMILES
Nc1ccccc1NC(=O)c1ccc(CNC(=O)OCc2cccnc2)cc1
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Compound Formula C21H20N4O3
Compound Structure
Protein Name
 Protein Info 
Histone deacetylase 3
Protein Classification
Epigenetic regulator
>
Eraser
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Histone deacetylase
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HDAC class I
Uniprot ID
O15379
Gene Name
HDAC3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 400 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2.3 nM
2 IC50 = 120 nM
3 IC50 = 310 nM
4 IC50 = 370 nM
5 IC50 = 400 nM
6 IC50 = 501 nM
7 IC50 = 590 nM
8 IC50 = 600 nM
9 IC50 = 605 nM
10 IC50 = 610 nM
11 IC50 = 624 nM
12 IC50 = 740 nM
13 IC50 = 830 nM
14 IC50 = 1000 nM
15 IC50 = 1230 nM
16 IC50 = 1700 nM
17 IC50 < 300 nM
18 Ki = 360 nM