Brief Information of the Compound and Protein
Compound Name
N-(3a,7a-dihydro-1H-indazol-5-yl)-4-(pyridin-4-ylmethylamino)isothiazole-3-carboxamide
    Show/Hide
PubChem ID
CID: 44591408
Canonical SMILES
O=C(NC1=CC2C=NNC2C=C1)c1nscc1NCc1ccncc1
    Show/Hide
Compound Formula C17H16N6OS
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 820 nM