Brief Information of the Compound and Protein
Compound Name
4-(pyridin-4-ylmethylamino)-N-(quinolin-2-yl)isothiazole-3-carboxamide
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PubChem ID
CID: 44591407
Canonical SMILES
O=C(Nc1ccc2ccccc2n1)c1nscc1NCc1ccncc1
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Compound Formula C19H15N5OS
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
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Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 770 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 440 nM