Brief Information of the Compound and Protein
Compound Name
4-(3,4-difluorobenzylamino)-N-(3-(trifluoromethyl)phenyl)isothiazole-3-carboxamide
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PubChem ID
CID: 44590993
Canonical SMILES
Fc1ccc(CNc2csnc2C(=O)Nc2cccc(c2)C(F)(F)F)cc1F
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Compound Formula C18H12F5N3OS
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 > 10000 nM