Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-(quinolin-4-ylmethylamino)-N-(3-(trifluoromethyl)phenyl)isothiazole-3-carboxamide
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 PubChem ID
CID: 44591117
Canonical SMILES
FC(F)(F)c1cccc(NC(=O)c2nscc2NCc2ccnc3ccccc23)c1
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Compound Formula C21H15F3N4OS
Compound Structure
Protein Name
 Protein Info 
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 390 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 110 nM