Brief Information of the Compound and Protein
Compound Name
N-(3-tert-butylphenyl)-4-(pyridin-4-ylmethylamino)-1,2-thiazole-3-carboxamide
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PubChem ID
CID: 44591376
Canonical SMILES
CC(C)(C)c1cccc(NC(=O)c2nscc2NCc2ccncc2)c1
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Compound Formula C20H22N4OS
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 82 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 35 nM
2 Ki = 120 nM
3 Ki = 130 nM