Brief Information of the Compound and Protein
Compound Name
5-(2,4-Dichloro-phenyl)-3-(1-phenyl-2-pyrrolidin-1-yl-ethyl)-3H-pyrimidin-4-one
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PubChem ID
CID: 44269822
Canonical SMILES
Clc1ccc(c(Cl)c1)-c1cncn(C(CN2CCCC2)c2ccccc2)c1=O
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Compound Formula C22H21Cl2N3O
Compound Structure
Protein Name
Kappa-type opioid receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Opioid receptor
Uniprot ID
P41145
Gene Name
OPRK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
ED50 = 615 nM
   TI
   LI
   LO
   TS
2
IC50 = 41 nM
   TI
   LI
   LO
   TS