Brief Information of the Compound and Protein
Compound Name
3-(5-Fluoro-2-methoxy-phenyl)-1-[2-(3-hydroxy-pyrrolidin-1-yl)-1-phenyl-ethyl]-1H-pyridin-2-one
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PubChem ID
CID: 44269994
Canonical SMILES
COc1ccc(F)cc1-c1cccn(C(CN2CCC(O)C2)c2ccccc2)c1=O
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Compound Formula C24H25FN2O3
Compound Structure
Protein Name
Kappa-type opioid receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Opioid receptor
Uniprot ID
P41145
Gene Name
OPRK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
ED50 = 32 nM
   TI
   LI
   LO
   TS
2
IC50 = 5.5 nM
   TI
   LI
   LO
   TS