Brief Information of the Compound and Protein
Compound Name
3-[1-[4-(3-nitrophenyl)phenoxy]-4-pyridin-4-ylbutan-2-yl]-1,3-diazinane-2,4-dione
    Show/Hide
PubChem ID
CID: 44352798
Canonical SMILES
[O-][N+](=O)c1cccc(c1)-c1ccc(OCC(CCc2ccncc2)N2C(=O)CCNC2=O)cc1
    Show/Hide
Compound Formula C25H24N4O5
Compound Structure
Protein Name
P2X purinoceptor 7
Protein Classification
Ion channel
>
Ligand-gated ion channel
>
P2X receptor
Uniprot ID
Q99572
Gene Name
P2RX7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1 Homo sapiens (Human)  1
1
IC50 = 630.96 nM
   TI
   LI
   LO
   TS