Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(1S,10R,11S,15S)-5-hydroxy-15-methyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-2,4,6-trien-14-one
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 PubChem ID
CID: 5870
SID: 49684201
Canonical SMILES
C[C@]12CC[C@H]3[C@@H](CCc4cc(O)ccc34)[C@@H]1CCC2=O
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Compound Formula C18H22O2
Compound Structure
Protein Name
 Protein Info 
Estrogen receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group A
>
Nuclear hormone receptor subfamily 3 group A member 1
Uniprot ID
P03372
Gene Name
ESR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 0.7 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  3
1
IC50 = 7.647 nM
   TI
   LI
   LO
   TS
2
IC50 = 96 nM
   TI
   LI
   LO
   TS
3
Ki = 2.185 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 7 nM
2 EC50 = 480 nM
3 IC50 = 29 nM
4 IC50 = 210 nM