Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[(3E)-4-(4-hydroxyphenyl)hex-3-en-3-yl]phenol
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 PubChem ID
CID: 448537
SID: 14848307
Canonical SMILES
CC\C(=C(\CC)c1ccc(O)cc1)c1ccc(O)cc1
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Compound Formula C18H20O2
Compound Structure
Protein Name
 Protein Info 
Estrogen receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group A
>
Nuclear hormone receptor subfamily 3 group A member 1
Uniprot ID
P03372
Gene Name
ESR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 = 0.11 nM
   TI
   LI
   LO
   TS
2
EC50 = 0.2 nM
   TI
   LI
   LO
   TS
CL000017 HeLa
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 0.06 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  4
1
IC50 = 0.77 nM
   TI
   LI
   LO
   TS
2
IC50 = 0.915 nM
   TI
   LI
   LO
   TS
3
Ki = 0.22 nM
   TI
   LI
   LO
   TS
4
Ki = 0.261 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 12 nM
2 IC50 = 0.33 nM
3 IC50 = 3 nM
4 Ki = 0.49 nM