Brief Information of the Compound and Protein
Compound Name
6-(4-Chloro-phenyl)-2,3,4,6-tetrahydro-pyrimido[2,1-a]isoindol-6-ol
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PubChem ID
CID: 12204576
Canonical SMILES
OC1(N2CCCN=C2c2ccccc12)c1ccc(Cl)cc1
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Compound Formula C17H15ClN2O
Compound Structure
Protein Name
Sodium-dependent serotonin transporter
Protein Classification
Transporter
>
Electrochemical transporter
>
SLC superfamily of solute carriers
>
SLC06 neurotransmitter transporter family
Uniprot ID
P31645
Gene Name
SLC6A4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL001019 HEK-hSERT Homo sapiens (Human)  1
1
Ki = 39 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 53 nM
   TI
   LI
   LO
   TS
2
Ki = 39 nM
   TI
   LI
   LO
   TS