Brief Information of the Compound and Protein
Compound Name
2-(2,5-Dimethoxy-4-trifluoromethyl-phenyl)-1-methyl-ethylamine
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PubChem ID
CID: 10400521
SID: 15417179
Canonical SMILES
COc1cc(c(OC)cc1CC(C)N)C(F)(F)F
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Compound Formula C12H16F3NO2
Compound Structure
Protein Name
5-hydroxytryptamine receptor 2A
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P14842
Gene Name
HTR2A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
EC50 = 68.4 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 2.2 nM