Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(7S,8R,11S)-11-Benzoyl-8-[3-(3,5-dibromo-phenyl)-propyl]-9-oxo-2-oxa-10-aza-bicyclo[11.2.2]heptadeca-1(16),13(17),14-triene-7-carboxylic acid hydroxyamide
    Show/Hide
 PubChem ID
CID: 10055393
SID: 15038914
Canonical SMILES
ONC(=O)[C@H]1CCCCOc2ccc(C[C@H](NC(=O)[C@@H]1CCCc1cc(Br)cc(Br)c1)C(=O)c1ccccc1)cc2
    Show/Hide
Compound Formula C32H34Br2N2O5
Compound Structure
Protein Name
 Protein Info 
Disintegrin and metalloproteinase domain-containing protein 17
Protein Classification
Enzyme
>
Protease
>
Metallo protease
>
Metallo protease MAM clan
>
Metallo protease M12B subfamily
Uniprot ID
P78536
Gene Name
ADAM17
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 > 5000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 87 nM